The explosion of Smart Communications in Network Technologies has resulted in the growing smart communications fields embedded in complex systems for a wide variety of applications in the future generation of network and cloud computing technologies. Indeed, autonomous systems embedded in complex configurations and dynamic environments have rapidly expanded from classical applications where different modular devices, actuators and sensors interact closely. This has considerably affected the control of a given system in a centralized manner. Current trends are to propose new autonomic architecture schemes that manage and control future emerging networks: sky of clouds, Internet of things, Smart Grids, Smart Cities, smart industry, etc. The evolution of Internet usages appeals for more quality guarantees in order to support stringent services. Aligned to these trends, the Open Data initiative fuels novel development scenarios, business opportunities and markets. In this context, for example, Healthcare and wellness applications such as helping elderly people, assisting dependent persons, habitat monitoring in a smart environment constitute some of the potential scenarios of convergence between autonomous systems and smart network technologies. These applications, which are based on high‐level commands, accomplish some specific tasks, reveal new challenges regarding mechanic design, portability, acceptability, power support and efficiency, control theory, cost, economic aspects, scalability, security, etc.The Special Issue focuses on the most recent advances in smart communications and Information Communication Technology networks impact not only on network technologies (protocols, equipment, algorithms, power, etc.), but also on creating collective and individual awareness about the multiple sustainability threats which our society is facing nowadays at social and environmental levels. This Special issue will bring together researchers from diverse fields and specialization, such as communication engineering, computer engineering, computer science, information technology, bio‐medical and mathematics. We invite researchers from industry, academia and government organization to discuss challenging ideas and novel research contributions, demonstrate results, and share standardization efforts on the smart communication embedded in autonomous systems and related areas.